All Around Joint Support

Chondroitin and Glucosamine have been shown to reduce one’s risk for colorectal cancer and may prove to reduce inflammation in the colon for those with colorectal cancer, a great addition to help with care. Both nutrients have also shown to help increase macrophage activity when coupled with Vitamin D, so their anti-cancer benefits need to be investigated.

Usually one thinks of joint support when Chondroitin and Glucosamine are mentioned. Their ability to increase synovial fluid production in large joints like the hips, knees, shoulders, and even the spinal joints, has proven to greatly reduce pain and increase joint motility in many patients.

The ingredients in Chondro-Flx provide full joint support, including integrity and movement, along with a normal inflammatory balance. The formula to this supplement also contains bromelain to enhance the absorption of chondroitin and vitamin C, an antioxidant that reduces free radicals and suppresses oxidative damage, along with being a cofactor to enzymes needed for the synthesis of new collagen.

Cartilage is composed of collagen fibers that maintain tensile strength, and proteoglycan molecules that serve as a cushion for joint impact. Proteoglycan molecules are made of a linear core protein that contains several molecules of glycosaminoglycans and the protein’s core molecules are attached to a hyaluronic acid framework. The breakdown of healthy cartilage is primarily caused by lifestyle factors and age, which leads to discomfort, along with nutrient and fluid deprivation of affected articular cartilage. Most current therapies combatting this issue fail to benefit the individual, as they inhibit the regeneration and elongation of chondroitin sulfate polymers that truly maintain joint health.

Orthomolecular states that, “Chondro-Flx combines glucosamine sulfate, chondroitin sulfate, vitamin C and bromelain, all of which have a long history of use and a large body of research highlighting their role in supporting joint health.” The main purpose for this supplement is to ultimately address the root cause of joint discomfort and provide the precursors to enhance cartilage synthesis in the body’s healthy joints and connective tissue.

Glucosamine, Synergy & Bromelain

Glucosamine sulfate is a naturally occurring, joint assisting compound and an important starting point for cartilage synthesis. Placebo studies have shown significant results in patients’ joint health and maintaining joint function. Supplementing with glucosamine boosts the health of joints and promotes joint comfortability, which contributes to a better quality of life. Synergy has shown significant results in placebo studies to show benefits to joint health in long-term results. Bromelain is a protease derived from pineapple stems that helps maintain a normal inflammatory balance in the body. Bromelain affects both the kinin and fibrin pathways, increasing the absorption of chondroitin sulfate.

Chondroitin Sulfate as CS b-Bioactive

Chondroitin sulfate is the major glycosaminoglycan associated with articular cartilage and is designed to hydrate joint tissues and allow for compression when pressure is put on the joint. There is a growing amount of research on this compound, specifically on the structural changes in patients’ knees. Chondroitin sulfate was shown to maintain normal inflammatory balance and have metabolic effects on synthesis of hyaluronate and cartilage proteoglycans. The study resulted in chondroitin sulfate being significantly superior to the placebo.

Bioavailability for Chondroitin Sulfate

When discussing bioavailability, it is important to note that not all elements or formulas of supplements are created equal. When sourcing key ingredients, cutting corners is not an option. Unfortunately, there are many products on the market that lack proper standards of ingredients used. In relation to chondroitin sulfate, it is important to notice the molecular weight, as this has a direct influence on its permeability and absorption. Many products containing chondroitin sulfate have particles that are inconsistent in size and are too large to be absorbed in the intestine. Chondro-Flx is enzymatically processed to provide consistently small, highly absorbed chondroitin molecules to ensure for the best results.