Anyone who has ever read any of my books knows that berberine is one of my favorite supplements for a variety of reasons. It is an essential cancer killer so I take it at least 4-5 times per week. It is also the best destroyer of H. pylori, the chief bacterial overgrowth that causes stomach issues and heart disease and it’s a great assistant to keep inflammation down in blood vessels as well.

Studies show that maintaining cardiovascular health is key for longevity and eventual success over critical diseases. Optimizing cardiovascular health, however, requires addressing metabolic factors to improve metabolism, stabilize mitochondria, and enhance insulin sensitivity. The ingredients in the CM Core formula do just that. Among their numerous benefits, berberine and alpha lipoic acid activate the master metabolic switch, adenosine mono-phosphate kinase (AMPK). This activation of this powerful metabolic enzyme triggers the very responses needed for metabolic support.

CM Core - a great source for Berberine and ALA 1
The CM Core formula has had numerous clinical studies to support its background, addressing several factors associated with ideal cardiometabolic health. The combination of berberine and alpha lipoic acid (ALA) helps maintain heart function, metabolism, antioxidant status, and lipid and glucose levels. CM Core optimizing cardiovascular and metabolic health due to its well-researched ingredients.

Berberine

Berberine is a plant extract used for centuries for its broad range of health-promoting properties. Berberine can be found in the roots and stems of plants such as Hyastatis Canadensis (goldenseal), Berberis aquifolium (Oregon grape) and Berberis vulgaris (barberry). Clinical trials have demonstrated that berberine administration supports cardiovascular health in a number of synergistic ways including maintaining blood pressure, supporting healthy heart contraction and rhythm and supporting healthy cholesterol levels. In several studies, berberine maintained healthy LDL cholesterol and triglyceride levels in the studied patients.

In addition to maintaining healthy lipid levels, berberine has also been shown to maintain healthy blood glucose levels through activation of AMPK. AMPK coordinates both the long-term and short-term metabolic changes and a reduction of energy storage. AMPK improves insulin sensitivity and decreases genes involved in fat storage while activating genes involved with burning fat. Activation of AMPK has been shown to stimulate the transcription factor involved in replicating mitochondria for increased metabolic potential.

Berberine also has the capability to promote the uptake of glucose through a mechanism that does not require insulin, allowing for better glucose within the cell. Studies have demonstrated that berberine’s metabolic support improves glucose tolerance and allows for the maintenance of balanced insulin levels, along with keeping healthy total cholesterol and triglyceride levels.

Alpha Lipoic Acid

Alpha lipoic acid (ALA) is a nutrient required for cellular metabolism, particularly the breakdown of carbohydrates and fatty acids. ALA has been shown to support blood sugar balance by activating AMPK, a major regulator of cellular energy. Research shows that ALA demonstrated support of healthy lipid levels while improving oxidative stress from reducing free radical damage. ALA also significantly improved glucose transport and utilization, while aiding in the regeneration of the body’s antioxidants including vitamin C, vitamin E and glutathione. Overall, ALA has the ability to maintain healthy blood vessel and circulatory health.