I have long since highlighted the therapeutic potential of curcumin (turmeric), used as a dietary ingredient and as a natural anti-inflammatory. It was shown to decrease the proliferative potential and induce the apoptosis potential of both androgen-dependent and androgen-independent prostate cancer cells in vitro, largely by modulating the apoptosis suppressor proteins and by interfering with the growth factor receptor signaling pathways as exemplified by the EGF-receptor.
A recent study stated, “Curcumin causes a marked decrease in the extent of cell proliferation.” Another study states that Curcumin, “interferes with prostate cancer proliferation and metastasis development through the down-regulation of androgen receptor and epidermal growth factor receptor, but also through the induction of cell cycle arrest. It regulates the inflammatory response through the inhibition of pro-inflammatory mediators and the NF-κB signaling pathway. These results are consistent with this compound’s ability to up-induce pro-apoptotic proteins and to down-regulate the anti-apoptotic counterparts.”
How much is Enough?
We typically recommend taking at least 1500 mg either taken WITH coconut oil OR pre-emulsified in a fat. We like DFH brand C3 as it is already emulsified in a fat. You MUST take curcumin with a fat!!! Cancer patients may want to take up to 5-8 grams throughout the day.