What Is DGL?

DGL, or deglycyrrhizinated licorice, is a form of licorice root that contains only biologically active flavonoids, without glycyrrhizin. The deglycyrrhized form of licorice allows for higher dosing of supportive flavonoids, which helps maintain a healthy mucosal surface in the stomach. DGL is traditionally used to support GL-related issues, but research has shown significance in promoting a bacterial balance and a healthy esophageal lining. Along with DGL, this formula includes aloe vera, slippery elm bark and marshmallow root, used to soothe the GI tract.

Throughout the United States, there are approximately 25 million people who will suffer from GI mucosal issues at some point in their lifetimes. Orthomolecular states that, “While such discomfort was originally thought to arise from stress, spicy foods, alcohol consumption, gastric acid production or heredity, today it is known that common bacteria from food is often the root cause. Since almost 80% of pathogens enter the body either through mucosal tissue or stay localized on mucosal surfaces, a healthy mucosal lining is of the utmost importance for digestive health.” What DGL does is supports gastrointestinal health by ultimately accelerating the secretion rate of mucus by the gastric and esophageal mucosa, which helps to protects tissues.


This formula includes GutGard,® which is a clinically studied form of deglycyrrhized licorice that provides improved control of glycyrrhized content and a rich source of flavonoids. Clinical trials have demonstrated that GutGard® made significant improvements to GI discomfort in comparison to the placebo.

Marshmallow Root & Slippery Elm Bark

Marshmallow root is a traditional irritation-relieving herb, having a historical significance of use in coating the gastric lining through its mucilage polysaccharides, which swell when mixed with liquid. This provides a soothing property to mucous membranes. The irritation relieving effect promotes a healthy mucosal surface in urinary tissues and membranes. In addition, marshmallow root promotes inflammatory process within the gastric mucosa. Slippery elm bark was traditionally used as a soothing herb for centuries. Slippery elm bark is rich in mucilage, which helps maintain normal inflammatory balance, which supports the GI tract.

Aloe Vera Concentrate

Aloe vera is similar to marshmallow root and slippery elm bark in that it is a soothing herb that has been historically used to maintain normal inflammatory balance. Significant studies have shown that aloe vera is beneficial to the gastric mucosa due to its ability to balance stomach acid levels and promote healthy mucus production. Other research has shown that aloe vera balanced gastric acid secretion and protected mucosa from temporary influxes of excess gastric acid.