About Vitamin C:

When orally consuming Vitamin C, regular physiological tissue concentrations act as an anti-oxidizing agent, protecting healthy cells from irregular replication and dis-ease.

The use of high-dose IV Vitamin C {IVC}, however, has been shown to act as an oxidizing agent, which is the same mechanism as chemotherapy and can contribute to significant tumor growth inhibition.

Vitamin C is chemically similar to glucose. Highly metabolic cancer cells uptake glucose much faster than normal/healthy cells.

Through IVC, tissue concentrations of ascorbic acid can reach levels as high as 20 mM {milleMolar} without being toxic to the patient or creating potential overdose scenarios.

Additional benefits to IV Vitamin C infusions include reducing systemic inflammation and inhibiting tumor angiogenesis {the formation of new blood vessels}.

Start Low & Slow:

Many practitioners try to get patients up to 75g/75,000mg of IV Vitamin C, delivered in a single dose over the course of an hour. But depending on age and body weight, 75g might be too high. So why go low & slow?

  1. In a worst-case scenario, a high dose IVC can clot veins and cause them to close. Smaller doses will allow the veins to remain open/healthy and not cause them to “burn out”.
  2. The only type of Vitamin C available through an IV is synthetic ascorbic acid, which is the outer shell of the vitamin C molecule. Although still effective, patients can experience mild side-effects {aka Herxheimer Reactions} from such a high dose of a synthetic nutrient.

Current research is also showing that patients do not need such a high dose to be effective.

According to the Riordan IVC protocol, calculations suggest that working up to a 50g infusion over the course of 1 hour would yield peak plasma concentration for producing reasonable anti-cancer effects.

Our Recommendation for a Starting Dose:

  • Dosage: 20g
  • Dosage Time: 1 Hour
  • Session Frequency: 1 per week
  • Maintain Frequency for 1 month/4 weeks

How to Safely Increase IV Vitamin C:

  • Increase dosage in 5g increments
  • After 1 month of 1x/week sessions, you can increase to 2 sessions per week for 2 weeks. Hold this frequency for 2-3 weeks and then increase, again, to 3 sessions per week. It is not necessary to do more than 3 sessions each week.
  • If, when increasing dosage or frequency, you feel worse after your infusion, drop back to your previous settings and hold for 2-3 more weeks. Then attempt slowly increasing again.


Each person’s body reacts to nutrients in different ways. Some people may be able to tolerate higher doses of IVC much more quickly than others.

If you are someone who is typically sensitive to new supplements or experiences detox reactions easily, then going slower might be the best course-of-action.

However if you feel your body can tolerate a higher dose of IV Vitamin C sooner than later, then trust your instincts and do what’s best for you.

Supplements to Take Alongside IV Vitamin C Infustions:

The therapeutic effects of IVC treatment can be enhanced by taking Vitamin K and Alpha-Lipoic Acid. ImmunoXYM by US Enzymes is available on the Conners Clinic web store and contains both vitamin K and ALA.

General recommended dosage: 2 capsules before IVC infusion and 2 capsules following IVC infusion.

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Following IV Vitamin C Treatments:

Drink plenty of water. This will help flush your kidneys and lymphatic system and help prevent a Herxheimer Reaction from occurring.

What to Expect from an IV Clinic:

Most clinics will require either a Letter of Recommendation or Prescription from your primary care physician. Conners Clinic can provide letters of recommendation only.

IV clinics may recommend combining IVC with IV Vitamin K3 {the synthetic form of vitamin K}. This is an acceptable addition as research studies show this may improve results.

IV Vitamin C and Amygdalin/Laetrile:

Be careful not to take excessively high doses of Amygdalin/Laetrile {B17} immediately prior to or following IVC therapy. Vitamin C is known to increase the in vitro conversion of amygdalin to cyanide and reduce body stores of cysteine, which is used to detoxify cyanide.