Gadolinium is a contrast dye used in MRI imaging. It is a heavy metal that is cleared through the liver via specific detoxification pathways. People with defects on these genetic pathways (NAT1/NAT2, PON1, CYP genes), those with a history of liver disease, and those with other liver clearing issues, are particularly susceptible to gadolinium toxicity issues. Gadolinium can be detected on urinary provocative testing using a oral chelation agent.

Recently, researchers from Finland, led by Dr. Aida Kiviniemi, found that gadolinium deposits can be detected in gliomas, a type of tumor that starts in the glial cells of the brain or the spine. Gliomas comprise about 30 percent of all brain tumors and central nervous system tumors, and 80 percent of all malignant brain tumors. The study also revealed that gadolinium deposits were found in adjacent normal brain cells, and necrotic tissue (dying cells).  The authors said that to their knowledge, “this is the first study to provide quantitative data of gadolinium retention in gliomas and neighboring normal brain with respect to tumor enhancement and type of GBCA used”.   “The levels of gadolinium in the tumor and normal brain correlated suggesting a possible transit of gadolinium to the surroundings of the brain lesion.  The most powerful predictor of gadolinium retention was the type of GBCA administered with significantly higher gadolinium accumulation detected with linear (gadodiamide and gadopentetate dimeglumine) relative to macrocyclic (gadoterate meglumine and gadobutrol) agents.” [1]

I would emphasize that, though gadolinium is a toxic metal and can be dangerous, not everyone exposed to the contrast agent is harmed. Like exposure to other toxins, every person detoxifies at different rates depending on the health of their detoxification pathways. There is also the argument that, without the contrasting dye, imaging can lack benefits and disease may be misdiagnosed. So, like all testing, there are positives and negatives and everyone must make their most educated decision. Perhaps a genetic workup might be prudent!

Detoxifying after an MRI is always a good idea. We recommend using a gadolinium homeopath at the very least. Utilizing chelating agents is another good way to assist in getting it out of your body as well. However, supporting the liver’s pathways is a must – supporting bile production through the addition of Phosphatidylcholine would be an example.


1. CleanseXym – Take 1-2 Capsules, three times per day in divided doses

2. SulforaXym – Take 2 Capsules per day in a divided dose

3. PON1 Assist – Take 2 Capsules per day in a divided dose

4. Body Bio PC – Take 2 Capsules per day in a divided dose


[1] Gadolinium retention in gliomas and adjacent normal brain tissue: association with tumor contrast enhancement and linear/macrocyclic agents, was recently published online in Neuroradiology.