Why Alpha-Lipoic Acid?

Alpha-lipoic acid (ALA) is a unique, vitamin-like antioxidant that can combat radiation sickness, repair damaged livers, treat diabetes and diabetes-related conditions (polyneuropathy) and protect against oxidative processes.

Unlike normal cells, tumor cells tend to survive in a redox environment where the elevated reactive oxygen species contribute to enhance cell proliferation (growth) and to suppress apoptosis. Alpha-lipoic acid, a naturally occurring reactive oxygen species scavenger, has been shown to possess anticancer activity, due to its ability to suppress proliferation and to induce apoptosis in different cancer cell lines.

One study showed evidence that ALA can effectively induce apoptosis in human colon cancer cells. Other studies support its use in the ancillary treatment of many diseases, such as diabetes, cardiovascular, neurodegenerative, autoimmune diseases, cancer and AIDS.

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The studies on this nutrient are abundant; it helps too many pathways to be left out of nearly any nutritional regimen.  Free radical damage can promote the activity of a particular cell protein called NF kappa B. (NF-kB).  NF-kB works to promote inflammation and genetic changes that have been linked with the development of cancer. Studies at the University of California at Berkley have found that when cells are bathed in ALA, NF-kB is inhibited thus preventing cell mutations from replicating. Researchers believe that this has significant implications in inhibiting the formation of cancerous tumors.

 

What we use to help induce apoptosis:

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