Pancreatic Cancer Growth

Recent research in mice and in human tissue samples has shown how pancreatic cancer cells can prevent starvation and continue growth by secreting its own nerve growth factor that triggers nerve cells to grow into the tumor mass and release serine. Serine, an amino acid, is needed to support pancreatic cancer cell survival and growth. Led by teams at NYU Grossman School of Medicine, the department of radiation oncology at NYU Langone Health, and Perlmutter Cancer Center, the studies also showed that pancreatic cancer growth in mice could be slowed, in part, with a low serine diet.

Pancreatic Cancer and A Low Serine Diet 1
“Our study offers more proof that pancreatic cancers are remarkable metabolic scavengers, which contributes to their deadliness,” said corresponding author Alec Kimmelman, MD, PhD, the Anita Steckler and Joseph Steckler chair of the department of radiation oncology at NYU Langone. “The ability of nerves to funnel nutrients from the bloodstream to the more austere pancreatic tumor microenvironment is a fascinating adaptation, and could lead to therapeutic approaches that interfere with this unique flexibility.”

This study again confirms what we’ve long stated that many cancers feed off proteins and the amino acids that make them up. Commonly, pancreatic cancers, liver and colon cancers fall into this groups but any cancer can prefer amino acids as fuel. Implementing a LOW SERINE diet is relatively simple to follow but might not be as easy for protein lovers. See the list of foods to avoid below:

Foods HIGH in serine to be AVOIDED:

  • Soybeans,
  • Nuts (especially peanuts, almonds, and walnuts),
  • Eggs,
  • Cheese,
  • Chickpeas,
  • Lentils, Kidney, Lima and Navy beans,
  • Meat,
  • Fish (especially shellfish)

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