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Point 9 for Cancer Success

Point 9 for Cancer Success

10 Points for Cancer - Point Nine: Inhibiting the 5-lipoxygenase (5-LOX) Enzyme

Your body has several inflammatory pathways. Inflammation, though typically labeled a negative process, is necessary to heal. It is prolonged, chronic inflammation that becomes a nuisance, and in cancer, it is something that we MUST deal with! The 5-lipoxygenase (5-LOX) enzyme is one inflammatory enzyme pathway that can contribute to the formation and progression of cancer. Arachidonic acid (AA)--a saturated fat found in high concentrations in meat and dairy products—promotes elevation of the 5-LOX enzyme. But remember, most every study revealing the negative effects of AA was performed with processed (non-organic, pasteurized…) AA which is caustic to your cells. This type of arachidonic acid is metabolized by 5-LOX to 5-HETE, a potent survival factor that cancer cells utilize to escape destruction. Therefore, non-organic, pasteurized dairy products and grain-fed (typical non-organic, store-bought) meats are NOT recommended for anyone, especially cancer patients.

In response to poor quality fat overload, the body increases its production of enzymes like 5-lipooxygenase (5-LOX) to degrade them and rid them from your body. Not only does 5-LOX directly stimulate cancer cell propagation, but the breakdown products that 5-LOX produces from poor quality fat overload (such as leukotriene B4, 5-HETE, and hydroxylated fatty acids) causes tissue destruction, chronic inflammation, and increased resistance of tumor cells to apoptosis (blocking programmed cell destruction).

Point 9 for Cancer Success

 

 

 

 

 

Specific extracts from the Boswelia plant selectively inhibit 5-lipoxygenase (5-LOX). In several well-controlled human studies, Boswelia has been shown to be effective in alleviating various chronic inflammatory. Scientists have discovered that the specific constituent in Boswelia responsible for suppressing 5-LOX is AKBA (3-O-acetyl-11-keto-B-boswellic acid). Boswelia-derived AKBA binds directly to 5-LOX and inhibits its activity. Good fats (from fish, borage, flax, and grass-fed meats) have been shown to block inflammatory pathways as well.

How to implement Point Nine

Decrease the consumption of poor quality fats such as grain-fed meats and pasteurized dairy products, along with high-glycemic carbohydrates (mainly grains and white potatoes).

Consider a Paleo-type diet.

Consider supplementing with the following nutrients to suppress 5-LOX enzyme activity:

  • Boswelia: (I use our own Clear Inflam that has everything one would need) 3-6 capsules daily
  • Ginger Root powder (I use our own Clear Inflam that has everything one would need) 3-6 capsules daily
  • PEOs - 3 teaspoons per day, Coconut oil (1-3 T/day)
  • Lycopene: 30mg daily with meals
  • Curcumin – again, I use OUR brand - CurcuClear as I believe that it is the most powerful form

As always, please do NOT use my book, website or newsletters as a substitute for getting properly tested for what is right for you.

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Conners Clinic is located on 8519 Eagle Point Blvd #170, Lake Elmo. From Minneapolis−Saint Paul International Airport (MSP) head southwest and continue onto Green Ln. Then keep right and slight right onto Glumack Dr. Next, keep right to stay on Glumack Dr and keep right at the fork and merge onto MN-5 W. After that merge onto MN-5 W and take the exit onto I-494 E. Take exit 58B to merge onto I-94 E toward Madison and take exit 250 for Radio Dr/Inwood Ave toward Washington County 13. Then use the left 2 lanes to turn left onto Inwood Ave N/Radio Dr. Finally, turn right onto Eagle Point Blvd, turn left at Eagle Point Cir and Conners Clinic will be on your right.

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For additional questions you can call us at (651) 739-1248

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